Living in Australia I would say that barely qualifies as a concerning spider

You would be surprised at how little they weigh actually!
OK - you will have to take the speaker down onto it's side, box edge down, lay a towel over the box edge, remove the screws from the ribbon fixing plates (the ones that go into the board), then carefully lower the ribbon frame to the towel over the box. From here - chasing the spider out will be easy - you may not even need to take the sock off. Use some cotton thread to prompt the spider to move if you do have to remove the sock (and of course full removal of the plates will be required - another 4 bolts).
Always good to avoid a bite - though I believe your local spiders are less of a concern than here!
Take care - Graz